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Coronary artery ectasia: its frequency and relationship with atherosclerotic risk factors in patients undergoing cardiac catheterization [Anatol J Cardiol]
Anatol J Cardiol. 2011; 11(4): 280-284 | DOI: 10.5152/akd.2011.076  

Coronary artery ectasia: its frequency and relationship with atherosclerotic risk factors in patients undergoing cardiac catheterization

Tolga Aksu1, Belma Uygur2, Mine Durukan Koşar3, Ümit Güray4, Nurcan Arat3, Şule Korkmaz4, Ayşe Çolak5
1Clinic of Cardiology, Kocaeli Derince Training and Research Hospital, Kocaeli-Turkey
2Clinic of Cardiology, Türkiye Yüksek İhtisas Education and Reseach Hospital, Ankara-Turkey
3Türkiye Yüksek İhtisas Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, Ankara-Türkiye
4Türkiye Yüksek İhtisas Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, Ankara, Türkiye
5Türkiye Yüksek İhtisas Hastanesi, Kardiyoloji Kliniği, Ankara-Türkiye

Objective: Coronary artery ectasia (CAE) is defined as local or generalized aneurysmal dilatation of the coronary arteries. We aimed to determine the frequency of CAE at our center and to compare clinical and angiographic characteristics between patients with isolated CAE and CAE with coronary artery disease (CAD). Methods: From February 2004 to December 2005, 12.514 patients were retrospectively analyzed by two independent operators who underwent coronary angiography. Coronary artery diameters were measured using qualitative computed angiography. CAD risk factors were recorded for all patients. Unpaired Student’s t-test and Chi-square test were used for statistical analysis. Results: CAE was diagnosed in 201 patients (1.59%). The majority (78%) were male. The mean age was 61±10.8 years (range, 25 to 82 years). The cases were divided into 2 groups as isolated CAE (Group 1) (14.9%) and CAE with CAD (Group 2) (85.1%). The risk factors of CAD were similar between two groups. The frequency of arterial involvement was: the right coronary artery (RCA) 54.3%; circumflex artery (Cx), 48.3%; the left anterior descending artery (LAD), 40.4%. CAE affected only one major vessel in 64.2% of cases and all 3 vessels in 9%. Isolated CAE was most commonly detected in Cx (47%). The type of CAE was determined according to Markis and Harikrishnan classification. The most prevalent involvement was Markis type 4 and Harikrishnan type 4a. Although atypical angina was the most common clinical presentation in both groups, acute coronary syndrome was more frequent in Group 2 (p=0.018). Conclusion: The risk factors of CAD and the manner of clinical presentation were considerably similar in both groups and this situation was consistent with similar etiopathogenesis of two diseases.

Keywords: Coronary ectasia, coronary artery disease


Tolga Aksu, Belma Uygur, Mine Durukan Koşar, Ümit Güray, Nurcan Arat, Şule Korkmaz, Ayşe Çolak. Coronary artery ectasia: its frequency and relationship with atherosclerotic risk factors in patients undergoing cardiac catheterization. Anatol J Cardiol. 2011; 11(4): 280-284


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