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The implications and requirements of transcatheter aortic valve replacement in low-risk patients [Anatol J Cardiol]
Anatol J Cardiol. 2020; 23(1): 2-9 | DOI: 10.14744/AnatolJCardiol.2019.39293  

The implications and requirements of transcatheter aortic valve replacement in low-risk patients

Emin Murat Tuzcu, Ahmad Edris
Department of Cardiology, Heart and Vascular Institute, Cleveland Clinic; Abu Dhabi-United Arab Emirates

Transcatheter aortic valve replacement (TAVR) is a transformative technology that has changed the management of patients with severe, symptomatic aortic stenosis. The use of TAVR in intermediate- to high-risk patients has been validated in several rigorously performed, randomized clinical trials. Recent studies using newer generation devices have demonstrated the noninferiority of TAVR as compared with surgical aortic valve replacement in low-risk patients, supporting the increased utilization and expansion of TAVR. The use of TAVR in low-risk patients has important implications and requires a multifaceted approach that includes a highly functional multidisciplinary heart team for careful patient selection; a need to understand and help mitigate certain key complications, such as stroke, paravalvular regurgitation, and conduction disturbances; careful data collection for continual outcome assessment and improvement; and the necessary expertize and procedural volume to maintain excellent outcomes and ensure optimal clinical care pathways.

Keywords: Transcatheter aortic valve replacement, surgical aortic valve replacement, aortic valve stenosis, risk factors, postoperative complications, treatment outcome.


Emin Murat Tuzcu, Ahmad Edris. The implications and requirements of transcatheter aortic valve replacement in low-risk patients. Anatol J Cardiol. 2020; 23(1): 2-9

Corresponding Author: Emin Murat Tuzcu, United Arab Emirates


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