The Anatolian Journal of Cardiology
Original Investigation

The effect of hemodialysis on right ventricular functions in patients with end-stage renal failure

1.

Clinic of Cardiology, Bursa Training and Research Hospital, Bursa

2.

Bezmialem Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, İstanbul

3.

Gemlik Devlet Hastanesi, Kardiyoloji Kliniği, Bursa

4.

1st Clinic of Cardiology, Bursa Subspecialization Training and Research Hospital, Bursa, Turkey

5.

Süleyman Demirel Üniversitesi Tıp Fakültesi, Kardiyoloji Ana Bilim Dalı Isparta, Türkiye

6.

Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, Bursa

Anatol J Cardiol 2012; 12: 5-10
DOI: 10.5152/akd.2012.002
Read: 215 Downloads: 142 Published: 01 July 2021

Objective: The aim of this study was to evaluate the effects of hemodialysis (HD) on right ventricular echocardiographic parameters in patients with end-stage renal failure (ESRF). Methods: Forty-three uremic patients who underwent echocardiography before and 30 minutes after dialysis included in this prospective obser- vational study. Right ventricular systolic function was evaluated using tricuspid annular plane systolic excursion (TAPSE) by M-mode echocar- diography and tricuspid lateral annular systolic velocity (Sa) by tissue Doppler echocardiography whereas diastolic function was evaluated using tricuspid early (E) and late (A) diastolic flow velocities by conventional and tricuspid lateral annular early (Ea) and late (Aa) diastolic velocities by tissue Doppler echocardiography. Myocardial performance index was taken as an indicator of global functions. Paired t test or Wilcoxon test were used for statistical analysis where appropriate. Results: E decreased significantly (68±13 cm/s and 56±12 cm/s before and after HD, respectively; p<0.0001) but A did not (p=0.797).TAPSE was 1.84±0.34 cm before HD and showed a significant increase to 2.03±0.20 cm after HD (p=0.006). Right ventricular MPI, Sa and Aa did not change significantly by dialysis (p=0.504; p=0.118 and p=0.150 respectively) whereas Ea decreased to 8.8±2.5 cm/s from 11.3±3.4 cm/s (p<0.001). Ea/Aa ratio also decreased significantly to 0.69±0.35 from 0.84±0.44 with HD (p=0.007). Conclusion: The results of this study indicates that parameters of right ventricular systolic function such as Sa and MPI are independent of preload whereas the conventional and tissue Doppler parameters of right ventricular diastolic function are preload dependent in patients with end-stage renal failure who undergo regular hemodialysis.

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ISSN 2149-2263 EISSN 2149-2271