The Anatolian Journal of Cardiology
Original Investigation - Heart Failure

Clinical characteristics and in-hospital outcomes of acute decompensated heart failure patients with and without atrial fibrillation


Department of Cardiology, Soma State Hospital; Manisa-Turkey


Departments of Cardiology, İstanbul University Institute of Cardiology; İstanbul-Turkey


Department of Cardiology, Faculty of Medicine, University of Health Sciences; Ankara-Turkey


Departments of Cardiology, Gülhane Military Medical Academy; Ankara-Turkey

Anatol J Cardiol 2020; 23: 260-267
DOI: 10.14744/AnatolJCardiol.2020.94884
Read: 342 Downloads: 159 Published: 01 July 2021

Objective: Atrial fibrillation (AF) and heart failure (HF) are common cardiovascular diseases. The impact of AF on in-hospital outcomes in acute decompensated heart failure (ADHF) is controversial. The aim of this study is to determine the prevalence of AF among hospitalized patients with ADHF and describe the clinical characteristics and in-hospital outcomes of these patients with and without AF. Methods: We examined the multicenter, observational data from the real-life data of hospitalized patients with HF: Journey HF-TR study in Turkey that studied the clinical characteristics and in-hospital outcomes of hospitalized patients with ADHF between September 2015 and September 2016. Results: Of the 1,606 patients hospitalized with ADHF, 626 (39%) had a history of AF or developed new-onset AF during hospitalization. The patients with AF were older (71±12 vs. 65±13 years; p<0.001) and more likely to have a history of hypertension, valvular heart disease, and stroke. The AF patients were less likely to have coronary artery disease and diabetes. In-hospital adverse event rates and length of in-hospital stay were similar in ADHF patients, both with and without AF. In-hospital all-cause mortality rate was higher in patients with AF than in patients without AF, although the difference was not statistically significant (8.9% vs. 6.8%; p=0.121). Conclusion: AF has been found in more than one-third of the patients hospitalized with ADHF, and it has varied clinical features and comorbidities. The presence of AF is not associated with increased adverse events or all-cause mortality during the hospitalization time.

ISSN 2149-2263 EISSN 2149-2271