The Anatolian Journal of Cardiology
Original Investigation

A seven-year single-center experience on AngioJet rheolytic thrombectomy in patients with pulmonary embolism at high risk and intermediate-high risk

1.

University Health Science, Kartal Koşuyolu Heart and Research Hospital, Department of Cardiology, İstanbul, Turkey

2.

Department of Cardiology, University of Health Sciences, Hamidiye Faculty of Medicine, Koşuyolu Yüksek İhtisas Training and Research Hospital; İstanbul-Turkey

3.

University of Health Sciences, Hamidiye Faculty of Medicine, Kosuyolu Heart, Education and Research Institute, Istanbul, Turkey

4.

University Health Science, Kartal Koşuyolu Heart and Research Hospital, Department of Anesthesiology, İstanbul, Turkey

5.

Department of Cardiology, Faculty of Medicine, Nişantaşı University; İstanbul-Turkey

6.

Department of Cardiology, Faculty of Medicine, Fırat University; Elazığ-Turkey

Anatol J Cardiol 2021; 25: 902-911
DOI: 10.5152/AnatolJCardiol.2021.28303
Read: 265 Downloads: 107 Published: 01 December 2021

Objective: AngioJet rheolytic thrombectomy (ART) has been used as a catheter-based treatment for acute pulmonary embolism (PE). In this study, based on our 7-year experience with ART in patients with PE, we evaluated the efficacy and safety outcomes of ART.

Methods: Our study is based on retrospective evaluation of 56 patients with high- and intermediate-high-risk PE, with an average age of 62 years [interquartile range (IQR) 50–73 years] who underwent ART.

Results: High and intermediate-high risks were noted in 21.4% and 78.6% of the patients, respectively. The ART duration was 304 (IQR: 246–468) seconds. Measures of obstruction, right to left ventricle diameter ratio, right to left atrial diameter ratio, and pulmonary arterial pressures were improved (p<0.001 for all). During the hospital stay, acute renal failure, major and minor bleeding, and mortality rates were 37.5%, 7.1%, 12.5%, and 8.9%, respectively. Aging related to post-procedural nephropathy while high-risk status was associated with in-hospital mortality (p=0.006) and long-term mortality.

Conclusion: ART resulted in significant and clinically relevant improvements in the pulmonary arterial thrombotic burden, right ventricle strain, and hemodynamics in patients with PE at high and intermediate-high risk. Aging increased the risk of post-procedural nephropathy, whereas baseline high-risk status predicted in-hospital and long-term mortality.

Cite this article as: Akbal ÖY, Keskin B, Tokgöz HC, Hakgör A, Karagöz A, Tanyeri S, et al. A seven-year single-center experience on AngioJet rheolytic thrombectomy in patients with pulmonary embolism at high risk and intermediate-high risk. Anatol J Cardiol 2021; 25: 902-11.

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ISSN 2149-2263 EISSN 2149-2271