The Anatolian Journal of Cardiology
Original Investigation

Classic and non-classic forms of mitral valve prolapse


Department of Cardiovascular and Thoracic Surgery, University Hospital of Thessaly, Larissa


Department of Cardiology, General Hospital of Kozani, Kozani city-Greece

Anatol J Cardiol 2012; 12: 2-4
DOI: 10.5152/akd.2012.001
Read: 210 Downloads: 124 Published: 01 July 2021

Objective: To investigate the significance of the established distinction between classic and non-classic forms of mitral valve prolapsed (MVP). Methods: We included in this prospective study all patients examined in our preventive cardiology outpatient clinics during the biannual period October 2004-October 2006. We examined in total 10.818 patients, 238 of whom (2.2%) were diagnosed for MVP. We noted relevant demograph- ic and clinical data (gender, age of diagnosis, symptoms, need for hospitalization) and performed statistical comparisons between patients with the classic and those with the non-classic form. Follow-up controls were performed three years afterwards. Results: Patients with the classic form had an earlier age of first diagnosis, more prominent symptoms, and more frequently diagnosis for other disorders (atrial septal defect, ventricular septal defect, Marfan syndrome, Ehlers-Danlos syndrome) than the rest of the patients; however, there were no significant differences as far as certain major complications (stroke, death, submission to surgery) were concerned. Conclusion: The classic form of mitral valve prolapse is more tightly associated with morbid complications, and a more frequent follow-up control in this group of patients may be useful.

ISSN 2149-2263 EISSN 2149-2271