ISSN 2149-2263 | E-ISSN 2149-2271 Home      
 
Volume : 22 Issue : 6
Current Issue Archive Popular Article Ahead of Print

   
Quick Search





 
The Anatolian Journal of Cardiology Association between serum adropin levels and isolated coronary artery ectasia in patients with stable angina pectoris [Anatol J Cardiol]
Anatol J Cardiol. 2019; 22(5): 250-255 | DOI: 10.14744/AnatolJCardiol.2019.90349  

Association between serum adropin levels and isolated coronary artery ectasia in patients with stable angina pectoris

Buğra Özkan1, Özcan Örsçelik1, Hatice Yıldırım Yaroğlu2, Şenay Balcı2, Mert Koray Özcan1, Ahmet Çelik1, Ismail Türkay Özcan1
1Department of Cardiology, Faculty of Medicine, Mersin University; Mersin-Turkey
2Department of Biochemistry, Faculty of Medicine, Mersin University; Mersin-Turkey

Objective: Dilation of one or more coronary artery segments to a diameter at least 1.5 times that of a normal adjacent segment is referred to as coronary artery ectasia (CAE). Adropin is a protein involved in endothelial function and is shown to have a protective effect on the regulation of cardiac functions. Atherosclerosis and endothelial dysfunction play an important role in the development of CAE. The aim of this study was to investigate the association between serum adropin levels and isolated CAE.
Methods: Patients with stable angina pectoris who underwent coronary angiography (CAG) between August 2017 and July 2018 were evaluated prospectively. A total of 92 subjects were included in the study-40 patients over 18 years old and diagnosed with isolated CAE based on CAG findings and a control group of 52 patients.
Results: Serum adropin level was found to be significantly lower in the isolated CAE group compared to the control group (1019.57 pg/mL and 1151.10 pg/mL, respectively, p=0.010). The isolated CAE group also exhibited a significantly higher mean platelet volume than that in the control group (10.75 fL and 10.17 fL, respectively, p=0.011).
Conclusion: Our results show that there is an association between low serum adropin level and isolated CAE.

Keywords: endothelial dysfunction, coronary artery ectasia, adropin


Buğra Özkan, Özcan Örsçelik, Hatice Yıldırım Yaroğlu, Şenay Balcı, Mert Koray Özcan, Ahmet Çelik, Ismail Türkay Özcan. Association between serum adropin levels and isolated coronary artery ectasia in patients with stable angina pectoris. Anatol J Cardiol. 2019; 22(5): 250-255

Corresponding Author: Buğra Özkan, Türkiye


TOOLS
Full Text PDF
Print
Download citation
RIS
EndNote
BibTex
Medlars
Procite
Reference Manager
Share with email
Share
Send email to author

Similar articles
PubMed
Google Scholar




 
 
KARE Publishing | Copyright © 2018 Turkish Society of Cardiology