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Comparison of traditional risk factors, natural history and angiographic findings between coronary heart disease patients with age <40 and ?40 years old [Anatol J Cardiol]
Anatol J Cardiol. 2007; 7(2): 124-127

Comparison of traditional risk factors, natural history and angiographic findings between coronary heart disease patients with age <40 and ?40 years old

Nesligül Yıldırım1, Nurcan Arat2, Mesut Sait Doğan3, Yeliz Sökmen4, Fırat Özcan5
1Department of Cardiology, Faculty of Medicine, Kırıkkale University, Kırıkkale-Turkey
2Department of Cardiology, Türkiye Yüksek İhtisas Hospital, Ankara, Turkey
3Department of Cardiology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak
4Departman of Cardiology, Türkiye Yüksek İhtisas Hospital, Ankara, Turkey
5Department of Cardiology, Yüksek İhtisas Education and Research Hospital, Ankara, Turkey

Objective: In this study we aimed to examine the angiographic findings, traditional risk factors and natural history of Turkish patients <40 and ≥40 years old with coronary heart disease (CHD). Methods: The records of 491 patients with stable angina pectoris or acute coronary syndrome (ACS), who had undergone coronary angiography (CAG) were reviewed. The patients <40 years (group 1) and ≥40 years (group 2) were compared. Results: The study population was classified as group 1 with 240 patients (mean age 35.7±3.4 years) and group 2 with 251 patients (mean age 61.0±9.7 years). Smoking, family history, hypercholesterolemia, hypertriglyceridemia and low levels of high-density lipoprotein cholesterol were more prevalent in group 1 while diabetes mellitus, hypertension was higher in group 2. The common presentation among <40 years patients was ACS whereas stable angina was the most common presentation in patients ≥40 years old. Patients in group 1 showed a preponderance of single-vessel disease whereas patients of group 2 showed dominance of multivessel disease. Early clinical course of patients with ACS in group 1 was better than in group 2. Conclusion: Our study shows a significantly different clinical, angiographic and biochemical profile in <40 years patients with CHD compared with ≥40 years patients. Dominance of smoking and dyslipidemias that are the preventable risk factors in premature CHD patients is an important threat for our community health. Healthy life styles should be encouraged beginning from young ages and new precautions about smoking must be taken.

Keywords: Coronary heart disease, young adults, old adults


Koroner arter hastası olan genç ve yaşlı hastaların risk faktörleri, klinik ve anjiyografi bulguları açısından karşılaştırılması

Nesligül Yıldırım1, Nurcan Arat2, Mesut Sait Doğan3, Yeliz Sökmen4, Fırat Özcan5
1Department of Cardiology, Faculty of Medicine, Kırıkkale University, Kırıkkale-Turkey
2Department of Cardiology, Türkiye Yüksek İhtisas Hospital, Ankara, Turkey
3Department of Cardiology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak
4Departman of Cardiology, Türkiye Yüksek İhtisas Hospital, Ankara, Turkey
5Department of Cardiology, Yüksek İhtisas Education and Research Hospital, Ankara, Turkey

Anahtar Kelimeler: Koroner arter hastalığı, genç erişkinler, yaşlı erişkinler


Nesligül Yıldırım, Nurcan Arat, Mesut Sait Doğan, Yeliz Sökmen, Fırat Özcan. Comparison of traditional risk factors, natural history and angiographic findings between coronary heart disease patients with age <40 and ?40 years old. Anatol J Cardiol. 2007; 7(2): 124-127


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