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Nitric oxide and cardiovascular system [Anatol J Cardiol]
Anatol J Cardiol. 2006; 6(4): 364-368

Nitric oxide and cardiovascular system

Atiye Çengel1
Department of Cardiology, Faculty of Medicine, Gazi University, Ankara, Turkey

Endothelium has many important functions including the control of blood-tissue permeability and vascular tonus, regulation of vascular sur- face properties for homeostasis and inflammation. Nitric oxide is the chief molecule in regulation of endothelial functions. Nitric oxide de- ficiency, which is also known as endothelial dysfunction, is the first step for the occurrence of many disease states in cardiovascular sys- tem including heart failure, hypertension, dyslipidemia, insulin resistance, diabetes mellitus, hyperhomocysteinemia and smoking. This re- view deals with the importance of nitric oxide for cardiovascular system. It also includes the latest improvements in the diagnosis and tre- atment of endothelial dysfunction.

Keywords: Nitric oxide, cardiovascular system


Atiye Çengel. Nitric oxide and cardiovascular system. Anatol J Cardiol. 2006; 6(4): 364-368


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