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The myocardial performance index in children with isolated left-to-right shunt lesions [Anatol J Cardiol]
Anatol J Cardiol. 2005; 5(2): 108-111

The myocardial performance index in children with isolated left-to-right shunt lesions

Tamer Baysal1, Bülent Oran2, Mustafa Doğan3, Derya Çimen4, Sevim Karaaslan4
1Department of Pediatric Cardiology, Meram Faculty of Medicine, Selcuk University, Konya-Turkey
2Selçuk Üniversitesi Meram Tıp Fakültesi, Çocuk Kardiyoloji Bilim Dalı, Konya-Türkiye
3From the Department of Pediatrics, Section of Pediatric Cardiology, Meram Medical Faculty, Selcuk University, Konya, Turkey
4Department of Pediatrics, Section of Pediatric Cardiology, Meram Medical Faculty, Selçuk University, 42080, Konya, Turkey

Objective: The myocardial performance index (MPI) measures the ratio of isovolumic time intervals to ventricular ejection time. The effects of altered ventricular preload or afterload on MPI have yet to be determined. This study was designed to determine the impact of altered preload on left and right ventricular myocardial performance index in the clinical setting of left-to-right lesions. Methods: The left and right ventricular myocardial performance indexes were measured in 17 patients with atrial septal defect (ages 6 to 148 months), 23 patients with ventricular septal defect (ages 2 to 160 months), and 24 healthy children (ages 3 to 160 months). A complete 2- dimensional and Doppler echocardiographic examination was performed in all study groups. Results: In patients with atrial septal defect, ventricular septal defect, and control group subjects, the left ventricular MPI was 0.38, 0.37 and 0.32, respectively, and the right ventricular MPI was 0.24, 0.21, and 0.20, respectively. No significant differences in the left and right ventricular myocardial performance indexes were seen between patients with left-to-right shunt lesions and control subjects. Conclusion: This study documents that the myocardial performance index is a quantitative measure of ventricular function that appears to be relatively independent of changes in preload.

Keywords: Myocardial performance index, children, left-to-right shunt lesions.


Tamer Baysal, Bülent Oran, Mustafa Doğan, Derya Çimen, Sevim Karaaslan. The myocardial performance index in children with isolated left-to-right shunt lesions. Anatol J Cardiol. 2005; 5(2): 108-111


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