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Circadian blood pressure pattern and cardiac autonomic functions: different aspects of same pathophysiology [Anatol J Cardiol]
Anatol J Cardiol. 2011; 11(2): 168-173 | DOI: 10.5152/akd.2011.031  

Circadian blood pressure pattern and cardiac autonomic functions: different aspects of same pathophysiology

Sercan Okutucu1, Uğur Nadir Karakulak2, Giray Kabakçı3
1Department of Cardiology, Faculty of Medicine, University of Hacettepe, Ankara Turkey
2Department of Cardiology, Faculty of Medicine, Hacettepe University, Ankara-Turkey
3Department of Cardiology Faculty of Medicine, Hacettepe University, Ankara-Turkey

Arterial blood pressure fluctuates with a pattern that follows a circadian rhythm, with a peak in the early morning hours and a trough during nighttime. Nocturnal dipping of arterial blood pressure is part of this normal circadian pattern, and its absence, which is called non-dipping is associated with more severe end-organ damage and increased risk of cardiovascular events, especially in hypertensive patients. Although pathologic mechanisms are still unclear, it has been suggested that non-dippers show impairment in the autonomic system functions that include abnormal parasympathetic and sympathetic activities. Several studies have examined the role of the autonomic nervous system in the non-dipping phenomenon. In this paper, we aimed to review the studies evaluating the relationship between circadian arterial blood pressure pattern and indices of cardiac autonomic functions.

Keywords: Autonomic nervous system, biological clocks, blood pressure, cardiovascular system, circadian rhythm, hypertension


Sercan Okutucu, Uğur Nadir Karakulak, Giray Kabakçı. Circadian blood pressure pattern and cardiac autonomic functions: different aspects of same pathophysiology. Anatol J Cardiol. 2011; 11(2): 168-173


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