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Snapshot evaluation of acute and chronic heart failure in real-life in Turkey: A follow-up data for mortality [Anatol J Cardiol]
Anatol J Cardiol. 2020; 23(3): 160-168 | DOI: 10.14744/AnatolJCardiol.2019.87894  

Snapshot evaluation of acute and chronic heart failure in real-life in Turkey: A follow-up data for mortality

Mehmet Birhan Yılmaz1, Emrah Aksakal2, Uğur Aksu2, Hakan Altay3, Yıldırım Nesligül4, Ahmet Çelik5, Mehmet Ata Akil6, Lütfü Bekar7, Mustafa Gökhan Vural8, Rengin Çetin Güvenç9, Savaş Özer10, Dilek Ural11, Yüksel Çavuşoğlu12, Lale Tokgözoğlu13
1Department of Cardiology, Faculty of Medicine, Dokuz Eylül University; İzmir-Turkey
2Department of Cardiology, Erzurum Regional Training and Research Hospital; Erzurum-Turkey
3Department of Cardiology, Faculty of Medicine, Başkent University; İstanbul-Turkey
4Department of Cardiology, Faculty of Medicine, Kırıkkale University; Kırıkkale-Turkey
5Department of Cardiology, Faculty of Medicine, Mersin University; Mersin-Turkey
6Department of Cardiology, Faculty of Medicine, Dicle University; Diyarbakır-Turkey
7Department of Cardiology, Faculty of Medicine, Hitit University; Çorum-Turkey
8Department of Cardiology, Faculty of Medicine, Sakarya University; Sakarya-Turkey
9Department of Cardiology, Haydarpaşa Numune Training and Research Hospital; İstanbul-Turkey
10Department of Cardiology, Recep Tayyip Erdoğan University Training and Research Hospital; Rize-Turkey
11Department of Cardiology, Faculty of Medicine, Koç University; İstanbul-Turkey
12Department of Cardiology, Faculty of Medicine, Eskişehir Osmangazi University; Eskişehir-Turkey
13Department of Cardiology, Faculty of Medicine, Hacettepe University; Ankara-Turkey

Objective: Heart failure (HF) is a progressive clinical syndrome. SELFIE-TR is a registry illustrating the overall HF patient profile of Turkey. Herein, all-cause mortality (ACM) data during follow-up were provided.
Methods: This is a prospective outcome analysis of SELFIE-TR. Patients were classified as acute HF (AHF) versus chronic HF (CHF) and HF with reduced ejection fraction (HFrEF), HF with mid-range ejection fraction, and HF with preserved ejection fraction and were followed up for ACM.
Results: There were 1054 patients with a mean age of 63.3±13.3 years and with a median follow-up period of 16 (7–17) months. Survival data within 1 year were available in 1022 patients. Crude ACM was 19.9% for 1 year in the whole group. ACM within 1 year was 13.7% versus 32.6% in patients with CHF and AHF, respectively (p<0.001). Angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, beta blocker, and mineralocorticoid receptor antagonist were present in 70.6%, 88.2%, and 50.7%, respectively. In the whole cohort, survival curves were graded according to guideline-directed medical therapy (GDMT) scores ≤1 versus 2 versus 3 as 28% versus 20.2% versus 12.2%, respectively (p<0.001). Multivariate analysis of the whole cohort yielded age (p=0.009) and AHF (p=0.028) as independent predictors of mortality in 1 year.
Conclusion: One-year mortality is high in Turkish patients with HF compared with contemporary cohorts with AHF and CHF. Of note, GDMT score is influential on 1-year mortality being the most striking one on chronic HFrEF. On the other hand, in the whole cohort, age and AHF were the only independent predictors of death in 1 year.

Keywords: heart failure, all-cause mortality, prognosis


Mehmet Birhan Yılmaz, Emrah Aksakal, Uğur Aksu, Hakan Altay, Yıldırım Nesligül, Ahmet Çelik, Mehmet Ata Akil, Lütfü Bekar, Mustafa Gökhan Vural, Rengin Çetin Güvenç, Savaş Özer, Dilek Ural, Yüksel Çavuşoğlu, Lale Tokgözoğlu. Snapshot evaluation of acute and chronic heart failure in real-life in Turkey: A follow-up data for mortality. Anatol J Cardiol. 2020; 23(3): 160-168

Corresponding Author: Mehmet Birhan Yılmaz, Türkiye


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