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The real-life data of hospitalized patients with heart failure: On behalf of the Journey HF-TR study investigators [Anatol J Cardiol]
Anatol J Cardiol. 2019; 21(1): 25-30 | DOI: 10.14744/AnatolJCardiol.2018.50880  

The real-life data of hospitalized patients with heart failure: On behalf of the Journey HF-TR study investigators

Ümit Yaşar Sinan1, Ahmet Ekmekçi2, Benay Özbay3, Filiz Akyıldız Akçay4, Lütfü Bekar5, Yavuzer Koza6, Ismail Bolat7, Umut Kocabaş8, Mehdi Zoghi3
1Department of Cardiology, Faculty of Medicine, İstanbul University, Institute of Cardiology; İstanbul-Turkey
2Department of Cardiology, Dr. Siyami Ersek Thoracic, Cardiac and Vascular Surgery Training and Research Hospital; İstanbul-Turkey
3Department of Cardiology, Faculty of Medicine, Ege University; İzmir-Turkey
4Department of Cardiology, Faculty of Medicine, İzmir Katip Çelebi University, Atatürk Training and Research Hospital; İzmir-Turkey
5Department of Cardiology, Faculty of Medicine, Hitit University; Çorum-Turkey
6Department of Cardiology, Faculty of Medicine, Atatürk University; Erzurum-Turkey
7Department of Cardiology, Fethiye State Hospital; Muğla-Turkey
8Department of Cardiology, Soma State Hospital; Manisa-Turkey

Objective: Acute heart failure (AHF) is a life-threatening clinical syndrome characterized by rapid onset of heart failure (HF) symptoms and signs and requires urgent therapy. The aim of the present study was to evaluate the overall clinical characteristics, management, and in-hospital outcomes of hospitalized patients with AHF in a large sample of Turkish population.
Methods: The Journey HF-TR study is a cross-sectional, multicenter, non-invasive and observational trial. Patients who were hospitalized with a diagnosis of AHF in the intensive care unit (ICU)/coronary care unit and cardiology wards between September 2015 and September 2016 were included in our study.
Results: A total of 1606 (male: 57.2%, mean age: 67.8±13 years) patients who were diagnosed with AHF were enrolled in the study. Seventeen percent of the patients were admitted to the hospital with a diagnosis of new onset AHF. Hypertension (67%) and coronary artery disease (CAD) (59.6%) were the most frequent underlying diseases. Acute coronary syndrome accompanying HF (14.7%), infection (29.3%), arrhythmia (25.1%), renal dysfunction (23%), and non-compliance with medication (23.8%) were the precipitating factors. The median length of stay in the ICU was 3 days (interquartile range, IQR 1–72) and 7 days (IQR 1–72) for in-hospital journey. The guideline recommended medications were less likely used in our patient population (<73%) before admission and were similar to European and US registers at discharge. The in-hospital mortality rate was 7.6%. Hypertension and CAD were the most frequent underlying diseases in our population similar to other European surveys. Although our study population was younger than other registers, in-hospital mortality was high.
Conclusion: Analyses of such real-world data will help to prepare a national database and distinctive diagnosis and treatment algorithms and to provide observing compliance with the current European Society of Cardiology guidelines for more effective management of HF.

Keywords: heart failure, length of stay, Turkey/national database, acute heart failure, mortality


Ümit Yaşar Sinan, Ahmet Ekmekçi, Benay Özbay, Filiz Akyıldız Akçay, Lütfü Bekar, Yavuzer Koza, Ismail Bolat, Umut Kocabaş, Mehdi Zoghi. The real-life data of hospitalized patients with heart failure: On behalf of the Journey HF-TR study investigators. Anatol J Cardiol. 2019; 21(1): 25-30

Corresponding Author: Ümit Yaşar Sinan, Türkiye


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