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The effect of inhibition of renin-angiotensin system on cardioversion success and recurrences of atrial fibrillation [Anatol J Cardiol]
Anatol J Cardiol. 2009; 9(6): 505-511

The effect of inhibition of renin-angiotensin system on cardioversion success and recurrences of atrial fibrillation

Abdullah Doğan1, Selahaddin Akçay2
1Department of Cardiology, Medical School, Suleyman Demirel University, Isparta, Turkey
2Süleyman Demirel Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Isparta, Türkiye

The renin-angiotensin system (RAS) can play an important role as the underlying mechanism for the development and recurrence of atrial fibrillation (AF). In addition, AF itself can lead to atrial structural and/or electrophysiologic remodeling by activating the RAS. This remodeling serves as an arrhythmogenic substrate for AF. Thus, the inhibition of RAS with angiotensin converting-enzyme inhibitor or angiotensin receptor blockers may be a strategy to prevent occurrence and recurrence of AF in certain patients such as those with heart failure and hypertension in associated with left ventricular hypertrophy. In addition, it may facilitate the cardioversion of AF. In this review, we overview the effect of RAS blockers on cardioversion success and recurrence of AF.

Keywords: Renin-angiotensin system, atrial fibrillation, cardioversion, recurrence


Abdullah Doğan, Selahaddin Akçay. The effect of inhibition of renin-angiotensin system on cardioversion success and recurrences of atrial fibrillation. Anatol J Cardiol. 2009; 9(6): 505-511


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