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Heart rate recovery, cardiac rehabilitation and erectile dysfunction in males with ischaemic heart disease [Anatol J Cardiol]
Anatol J Cardiol. 2016; 16(4): 256-263 | DOI: 10.5152/AnatolJCardiol.2015.6122  

Heart rate recovery, cardiac rehabilitation and erectile dysfunction in males with ischaemic heart disease

Dariusz Kalka1, Zygmunt Domagala4, Leslaw Rusiecki2, Lukasz Karpinski3, Jana Gebala3, Piotr Koleda2, Malgorzata Rusiecka5, Bohdan Gworys4, Witold Pilecki2
1Cardiosexology Unit, Department Of Pathophysiology, Wroclaw Medical University; Ul. K. Marcinkowskiego 1; Wroclaw- Poland; Centre For Men’s Health Ýn Wroclaw- Poland
2Cardiosexology Unit, Department Of Pathophysiology, Wroclaw Medical University; Ul. K. Marcinkowskiego 1; Wroclaw- Poland
3Centre For Men’s Health Ýn Wroclaw- Poland
4Department Of Anatomy, Wroclaw Medical University, Ul. T. Chalubinskiego 6a, Wroclaw- Polan
5Department Of Gynaecological Oncology, Wroclaw Medical University; Pl. L. Hirszfelda 12; Wroc Ł Aw- Poland

Objective: Heart rate recovery (HRR) is a recognised marker used in clinical practice for assessing the risk of sudden cardiac death. Physical exercise leads to an improvement in HRR and has a proven beneficial effect on erection quality (EQ) related to the activity of the autonomic nervous system in men with ischaemic heart disease (IHD). This paper evaluates the relationship between HRR and EQ in patients with IHD and erectile dysfunction (ED) who underwent cardiac rehabilitation.
Methods: The main analysis was based on the Mann–Whitney U test, Wilcoxon signed-rank test, Spearman correlation coefficient, Pearson's chi-square test, chi-square test, with the Yates correction and (if possible) parametric tests were used. This prospective, non-randomised intervention study included 124 men with IHD and ED [International Index of Erectile Function (IIEF-5) scores of ≤21]. Of these, 89 patients underwent a 6-month cardiac rehabilitation phase III programme, whereas 35 did not. The results of the participants’ total IIEF-5 scores and their HRR, demographic and clinical data were analysed.
Results: The results of the 89 rehabilitated patients (mean age: 60.44±9.29 years) and 35 controls (mean age: 61.43±8.81 years) were analysed. In the rehabilitated patients, the mean baseline IIEF-5 score was 13.15±5.76 (95% CI: 11.93–14.36) and HRR was 16.49±7.68/min (95% CI: 14.88– 18.11). After cardiac rehabilitation, the parameters of ED and HRR improved significantly and were significantly higher than those of the controls; the mean IIEF-5 score of the rehabilitated group increased to 15.36±6.51 (95% CI: 13.99–16.73), while HRR increased to 21.40±7.25/min (95% CI: 19.88–22.93). A significant correlation was found between ΔHRR and ΔEQ (r=0.409791) as a result of the 6-month cardiac training programme
Conclusion: Cardiac rehabilitation assessed by HRR has a sizable effect on autonomic balance in patients with IHD and ED, which plays a significant role in the mechanism of erection improvement. (Anatol J Cardiol 2016; 16: 256-63)

Keywords: cardiac rehabilitation, heart rate recovery, erectile dysfunction, ischaemic heart disease


Dariusz Kalka, Zygmunt Domagala, Leslaw Rusiecki, Lukasz Karpinski, Jana Gebala, Piotr Koleda, Malgorzata Rusiecka, Bohdan Gworys, Witold Pilecki. Heart rate recovery, cardiac rehabilitation and erectile dysfunction in males with ischaemic heart disease. Anatol J Cardiol. 2016; 16(4): 256-263

Corresponding Author: Dariusz Kalka, Poland


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