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PISA method for assessment of mitral regurgitation in children [Anatol J Cardiol]
Anatol J Cardiol. 2005; 5(3): 167-171

PISA method for assessment of mitral regurgitation in children

Osman Başpınar1, Sevim Karaaslan2, Bülent Oran3
1Department of Pediatric Cardiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
2Selçuk Üniversitesi Meram Tıp Fakültesi, Çocuk Kardiyoloji Bilim Dalı, Konya-Türkiye
3Department of Pediatrics, Section of Pediatric Cardiology, Meram Medical Faculty, Selçuk University, 42080, Konya, Turkey

Objective: The purpose of this study was to determine the feasibility and significance of the proximal isovelocity surface area (PISA) method in children with rheumatic mitral regurgitation (MR). Methods: Thirty-one children (mean age 12.3±3.1 years), with chronic MR, were evaluated by semiquantitative and quantitative Doppler, quantitative two-dimensional echocardiography and the PISA methods. Also, we compared the effective regurgitant orifice area, regurgitation volume and systolic left ventricular functions in mild-moderate and severe MR. Results: There were no statistically significant differences in the regurgitant orifice area and regurgitant volume values obtained by the PISA method and the quantitative Doppler (p>0.05) but they were different from the same values obtained by two dimensional echocardiography (p<0.05). There were excellent correlations between the regurgitant orifice area, regurgitant volume and the radius of the proximal flow convergence hemisphere (r=0.882, r=0.925, r=0.880; p<0.05). We found a very good correlation between the regurgitant orifice area obtained by the PISA and left ventricular end-diastolic diameters, the ratio of the jet/left atrial area, grading with color Doppler imaging (r=0.763, r=0.745, r=0.618; p<0.05). Conclusion: It is concluded that MR can be accurately predicted in children by using the PISA method as like as the Doppler method.

Keywords: The proximal isovelocity surface area, mitral regurgitation, childhood


Osman Başpınar, Sevim Karaaslan, Bülent Oran. PISA method for assessment of mitral regurgitation in children. Anatol J Cardiol. 2005; 5(3): 167-171


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